In-House Synthesis and Characterization of Vitamin C and Glycerine Based Natural Deep Eutectic Solvent

This study introduces an innovative Natural Deep Eutectic Solvent (NADES) based on Vitamic C (L-Ascorbic acid) and glycerine, delving into its synthesis, thermophysical characterization, and potential applications. A comprehensive exploration of thermophysical properties, including density, pH, surface tension, refractive index, and viscosity, was conducted. Fourier Transform Infrared (FTIR) analysis was employed to gain insights into the molecular composition, revealing the emergence of new bonds within the NADES structure. Thermogravimetric Analysis (TGA) indicated notable weight loss post-180°C, primarily attributed to glycerin degradation. The nonlinear reduction in surface tension, refractive index, and viscosity with temperature underscores the adaptability of Ascorbic acid-based NADES for diverse industrial applications. Potential areas of utilization include pharmaceuticals as a solvent for enhancing drug solubility and stability, biotechnology in enzyme stabilization and biocatalysis, cosmetics as an antioxidant in skincare formulations, the food industry as a natural preservative and antioxidant, and environmental remediation for the extraction of heavy metals and organic pollutants. The environmentally friendly and low-toxicity characteristics of NADES position them as promising and sustainable alternatives. Nevertheless, further research and development are crucial to fine-tune their performance and customize properties to meet specific industrial requirements.