Comparative characteristics of the "Iodezol" drug study on SPEV and BHK-21/C13 cell culture and Tetrahymena pyriformis infusoria culture

Control of the toxicity of biocidal drugs prevents negative effects on organs and tissues, the occurrence of side effects, and facilitates the determination of optimal safe doses, methods, and frequency of use, which contributes to the effective implementation of drugs. Studies on the toxicity of the biocidal agent “Iodezol” were conducted under conditions of protein loading in SPEV and BHK-21/C13 cell cultures at 0.1, 0.3, 0.5, and 1.0 % concentrations at exposure for 30 and 60 minutes. To compare the toxicity and harmfulness of the biocidal preparation “Iodezol” in the same concentrations, the experiments on the simplest test organisms, infusoria Tetrahymena pyriformis, were determined in experiments on the simplest test organisms. The results of the study showed that the biocidal agent “Iodezol” is not toxic to the transplanted cell cultures of SPEV and BHK-21/C13 in 0.1, 0.3% concentrations. The maximum permissible levels of working solutions of 0.1 and 0.3 % concentrations of the biocidal agent “Iodezol” were established according to the indicators of vital activity of infusoria