Clinical characteristics of EGFR-ctDNA shedders in EGFR-mutant NSCLC patients
Our preliminary data demonstrate that specific clinical characteristics predict mEGFR shedding in ctDNA of NSCLC, suggesting a potential clinical applicability for understanding potential false negative results and appropriate reporting in clinical practice.
Authors
- Martina Ruglioni (ORCID: https://orcid.org/0000-0002-3186-9003)
- Andrea Sbrana (ORCID: https://orcid.org/0000-0003-4460-5282)
- Iacopo Petrini (ORCID: https://orcid.org/0000-0002-7752-6866)
- Marzia Del Re (ORCID: https://orcid.org/0000-0001-7343-6161)
- Antonio Chella (ORCID: https://orcid.org/0000-0002-8625-708X)
- Stefania Crucitta (ORCID: https://orcid.org/0000-0002-5046-9048)
- Christian Diego Rolfo (ORCID: https://orcid.org/0000-0002-7860-8417)
- Romano Danesi (ORCID: https://orcid.org/0000-0002-4414-8934)
- Giovanna Irene Luculli (ORCID: https://orcid.org/0009-0006-7060-7088)
- Leila Sadeghi Gol
- C. Braço Forte
Institutions
- University of Pisa (IT)
- University of Milan (IT)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- Agostino Gemelli University Polyclinic (IT)
- Saint Camillus International University of Health and Medical Sciences (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1016/j.tranon.2024.102228
- Citations
- 5
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Ministero dell’Istruzione, dell’Università e della Ricerca
- Ministero dell'Università e della Ricerca