Automated CT‐based measurements of radial and longitudinal expansion of airways due to breathing‐related lung volume change
Our CT-based automated measures of breathing-related radial and longitudinal expansion of airways are repeatable and in agreement with manually derived values. Automation of different airway mechanical biomarkers and their observed significant associations with age, sex, BMI, smoking, and COPD severity establish an effective tool to investigate multi-pathway impairments of respiratory mechanics in COPD and other lung diseases.
Authors
- Eric A. Hoffman (ORCID: https://orcid.org/0000-0001-8456-9437)
- Sean B. Fain (ORCID: https://orcid.org/0000-0001-5461-0646)
- Punam K. Saha (ORCID: https://orcid.org/0000-0003-1576-118X)
- Syed Ahmed Nadeem (ORCID: https://orcid.org/0000-0002-5933-3825)
- Alejandro P. Comellas (ORCID: https://orcid.org/0000-0003-1521-7520)
- Kung‐Sik Chan
Institutions
- University of Iowa (US)
Publication Details
- Journal
- Medical Physics
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1002/mp.17592
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute