Global collaboration between platform trials in surgery and anaesthesia
Large, randomized trials are the bedrock of evidence-based medicine, but the resources required to complete such trials greatly limit the number of important clinical questions that can be addressed within a reasonable period of time. Adaptive platform trials can identify effective, ineffective, or harmful treatments faster. These trials have been shown to deliver rapid evidence through the COVID-19 pandemic and are now being adopted across surgery and anaesthesia, with many opportunities for surgeons, anaesthetists, and other perioperative physicians to conduct and collaborate in platform trials.
Authors
- Trisha Peel (ORCID: https://orcid.org/0000-0003-2370-2438)
- Paul S. Myles (ORCID: https://orcid.org/0000-0002-3324-5456)
- James Glasbey (ORCID: https://orcid.org/0000-0001-7688-5018)
- Thomas Pinkney (ORCID: https://orcid.org/0000-0001-7320-6673)
- Steve Webb
Institutions
- University Hospitals Birmingham NHS Foundation Trust (GB)
- The Alfred Hospital (AU)
- Victoria University of Wellington (NZ)
- St John of God Hospital (AU)
- Monash University (AU)
- University of Birmingham (GB)
Publication Details
- Journal
- British journal of surgery
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1093/bjs/znae262
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Handicapped Research
- National Institute for Health and Care Research
- Department of Health and Social Care
- Monash University
- National Health and Medical Research Council