[One new galloyl derivative from Isodon henryi].

Seven compounds(1-7) were isolated from Isodon henryi through silica gel, Sephadex LH-20, ODS, MCI column chromatography and semi-preparative HPLC. Their structures were identified as isogallicacid(1), caffeic acid(2), syringic acid(3), protocatechuic acid(4), oresbiusin A(5), lophanthoside A(6), and 8-hydroxypinoresinol(7), by spectroscopic techniques including HR-MS, IR, UV, NMR, and ECD. Compound 1 was a new galloyl derivative. Moreover, it demonstrated a significant inhibitory effect on the lipopolysaccharide-induced release of nitric oxide from RAW264.7 cells.

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Publication Details

Journal
PubMed
Published
2024-11-01
DOI
https://doi.org/10.19540/j.cnki.cjcmm.20240806.201
Primary Topic
Bioactive Natural Diterpenoids Research
Type
article
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article

[One new galloyl derivative from Isodon henryi].

Liping Dai, Jun Chi, Zhimin Wang, Yixiao Li
PubMed
Bioactive Natural Diterpenoids Research
article

[One new galloyl derivative from Isodon henryi].

Liping Dai, Jun Chi, Zhimin Wang, Yixiao Li
article en

Abstract

Seven compounds(1-7) were isolated from Isodon henryi through silica gel, Sephadex LH-20, ODS, MCI column chromatography and semi-preparative HPLC. Their structures were identified as isogallicacid(1), caffeic acid(2), syringic acid(3), protocatechuic acid(4), oresbiusin A(5), lophanthoside A(6), and 8-hydroxypinoresinol(7), by spectroscopic techniques including HR-MS, IR, UV, NMR, and ECD. Compound 1 was a new galloyl derivative. Moreover, it demonstrated a significant inhibitory effect on the lipopolysaccharide-induced release of nitric oxide from RAW264.7 cells.

PubMedVol. 49(21)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), China Academy of Chinese Medical Sciences (CN), First Affiliated Hospital of Henan University (CN), Sichuan Academy of Traditional Chinese Medicine (CN)
Clean water and sanitation
Bioactive Natural Diterpenoids Research
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