Epidermal growth factor receptor ligands enriched in follicular fluid exosomes promote oncogenesis of fallopian tube epithelial cells
Our results demonstrate that FF exosomes serve as carriers of EGFR ligands as well as ligands of other RTKs that mediate the transformation of FTE cells and underscore the need to further explore the content and roles of FF exosomes in HGSC development.
Authors
- Pao‐Chu Chen (ORCID: https://orcid.org/0000-0003-2350-9873)
- Sung‐Chao Chu (ORCID: https://orcid.org/0000-0002-2737-0787)
- Tang‐Yuan Chu (ORCID: https://orcid.org/0000-0003-2717-2681)
- Aye Aye Khine (ORCID: https://orcid.org/0009-0005-9472-0950)
- Hsuan-Shun Huang
- Ying-Hsi Chen
Institutions
- Tzu Chi College of Technology (TW)
- Tzu Chi University (TW)
- Tzu Chi Foundation (TW)
- Taiwan Hospitality and Tourism University (TW)
- National Dong Hwa University (TW)
- Buddhist Tzu Chi General Hospital (TW)
- Hualien Tzu Chi Medical Center (TW)
- Buddhist Tzu Chi Medical Foundation (US)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1186/s12935-024-03614-9
- Citations
- 8
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.30
Funders
- National Health Research Institutes
- Buddhist Tzu Chi Medical Foundation
- National Science and Technology Council
- Buddhist Tzu Chi Hospital
- Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation