Impact of excess sugar on the whole genome DNA methylation pattern in human sperm
In human sperm, DNA methylation levels were linked to gene expression, and excess sugar had modest effects on methylation on imprinted and highly expressed genes, and genes affecting fertility.
Authors
- Alexander Perfilyev (ORCID: https://orcid.org/0000-0003-1136-8946)
- Stephan Ruhrmann (ORCID: https://orcid.org/0000-0002-6022-2364)
- Jones K. Ofori (ORCID: https://orcid.org/0000-0001-6484-1544)
- Unn Kugelberg
- Tina Rönn (ORCID: https://orcid.org/0000-0001-7622-800X)
- Josefine Jönsson (ORCID: https://orcid.org/0000-0003-0709-2828)
- Signe Skog (ORCID: https://orcid.org/0000-0002-7590-8326)
- Charlotte Ling (ORCID: https://orcid.org/0000-0003-0587-7154)
- Anita Öst (ORCID: https://orcid.org/0000-0003-0547-1904)
- Karl Bacos (ORCID: https://orcid.org/0000-0002-2461-9073)
- Axel Lindström (ORCID: https://orcid.org/0009-0008-1641-0406)
Institutions
- Linköping University (SE)
- Scania (Sweden) (SE)
- Lund University (SE)
Publication Details
- Journal
- Epigenomics
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1080/17501911.2024.2439782
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Stiftelsen för Strategisk Forskning
- Lunds Universitet
- Knut och Alice Wallenbergs Stiftelse
- Novo Nordisk
- Vetenskapsrådet
- Science for Life Laboratory
- Skånes universitetssjukhus