Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification

Huda et al. (https://doi.org/10.1083/jcb.202406170) reveal a transient, cell cycle-dependent increase in PI(3,5)P2 levels at the lysosome-like vacuole of yeast daughter cells. The resulting lipid asymmetry alters vacuolar pH in both daughter and mother cells and will impact multiple downstream functions.

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Publication Details

Journal
The Journal of Cell Biology
Published
2024-12-20
DOI
https://doi.org/10.1083/jcb.202412054
Primary Topic
Cellular transport and secretion
Type
article
Field-Weighted Citation Impact
0.00

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article

Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification

Patricia M. Kane
The Journal of Cell Biology
Cellular transport and secretion
article

Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification

Patricia M. Kane
article en

Abstract

Huda et al. (https://doi.org/10.1083/jcb.202406170) reveal a transient, cell cycle-dependent increase in PI(3,5)P2 levels at the lysosome-like vacuole of yeast daughter cells. The resulting lipid asymmetry alters vacuolar pH in both daughter and mother cells and will impact multiple downstream functions.

The Journal of Cell BiologyVol. 224(1)
SUNY Upstate Medical University (US)
National Institutes of Health
Openalex Percentile: Top 75%
Cellular transport and secretion
DOIOpen Access PDFOpenAlex
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Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification — Patricia M. Kane · The Journal of Cell Biology (2024) | TGRS Research Map | TGRS