Diffusion weighted imaging for improving the diagnostic performance of screening breast MRI: impact of apparent diffusion coefficient quantitation methods and cutoffs
Our findings demonstrate that with appropriate ADC thresholds, comparable reduction in benign biopsies can be achieved using lesion ADC measurements computed from a variety of approaches. Choice of ADC cutoff depends on ROI approach and preferred performance tradeoffs (biopsy reduction vs sensitivity).
Authors
- Debosmita Biswas (ORCID: https://orcid.org/0000-0002-0798-5637)
- Habib Rahbar (ORCID: https://orcid.org/0000-0003-4835-1478)
- Isabella Li
- Daniel S. Hippe (ORCID: https://orcid.org/0000-0003-2427-4404)
- Andrea M. Winter (ORCID: https://orcid.org/0000-0003-4075-1047)
- Savannah C. Partridge
Institutions
- University of Washington (US)
- Fred Hutch Cancer Center (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fonc.2024.1437506
- Citations
- 2
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Institutes of Health
- National Cancer Institute