Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer
Our findings suggest that the potentiating effect of 3-IAA observed in metastatic PDAC undergoing chemotherapy may not translate to borderline resectable or locally advanced PDAC. We recommend additional clinical validation of 3-IAA's predictive value in different categories of PDAC before implementation attempts in human studies are initiated.
Authors
- Elin H. Kure (ORCID: https://orcid.org/0000-0002-5135-9916)
- Adrian McCann (ORCID: https://orcid.org/0000-0002-5728-5321)
- Sheraz Yaqub (ORCID: https://orcid.org/0000-0002-5696-2319)
- Peder R. Braadland (ORCID: https://orcid.org/0000-0002-0794-7737)
- Per Magne Ueland (ORCID: https://orcid.org/0000-0002-1903-0571)
- Knut Jørgen Labori (ORCID: https://orcid.org/0000-0001-6777-7955)
- Ingvild Farnes (ORCID: https://orcid.org/0009-0002-7738-7787)
- Johannes R. Hov (ORCID: https://orcid.org/0000-0002-5900-8096)
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
- University of South-Eastern Norway (NO)
- Bevital (Norway) (NO)
- University of Bergen (NO)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fonc.2024.1488749
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.57