Specific functions and therapeutic applications of microRNAs in aging and age-related diseases

Aging is a complex process causing organ dysfunction and chronic diseases.This review explores the roles of microRNAs (miRNAs) in aging and related diseases.miRNAs regulate biological processes and are emerging as biomarkers for diagnosis and therapy.Age-related changes in miRNA expression, such as miR-34a and miR-29b, influence tissue damage and inflammation.These miRNAs are critical in aging-related disease mechanisms, offering insights for prediction and treatment.This review highlights miRNAs' significance in understanding aging and suggests their potential for innovative therapies and diagnostics.

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Publication Details

Journal
Journal of Applied Biological Chemistry
Published
2024-12-20
DOI
https://doi.org/10.3839/jabc.2024.062
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
0.00

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article

Specific functions and therapeutic applications of microRNAs in aging and age-related diseases

Heedoo Lee, Dohyun Kim, Nayoung Lee
Journal of Applied Biological Chemistry
MicroRNA in disease regulation
article

Specific functions and therapeutic applications of microRNAs in aging and age-related diseases

Heedoo Lee, Dohyun Kim, Nayoung Lee
article en

Abstract

Aging is a complex process causing organ dysfunction and chronic diseases.This review explores the roles of microRNAs (miRNAs) in aging and related diseases.miRNAs regulate biological processes and are emerging as biomarkers for diagnosis and therapy.Age-related changes in miRNA expression, such as miR-34a and miR-29b, influence tissue damage and inflammation.These miRNAs are critical in aging-related disease mechanisms, offering insights for prediction and treatment.This review highlights miRNAs' significance in understanding aging and suggests their potential for innovative therapies and diagnostics.

Journal of Applied Biological ChemistryVol. 67
Changwon National University (KR)
Changwon National University
Zero hunger
Openalex Percentile: Top 67%
MicroRNA in disease regulation
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