Exploration of molecular biomarkers in ankylosing spondylitis transcriptomics
This study identified key genes that may reveal a potential association between AS and ferroptosis, demonstrating high diagnostic value. Furthermore, the expression levels of these genes in peripheral blood mononuclear cells (PBMCs) are strongly correlated with disease activity. These findings not only suggest potential biomarkers for the diagnosis of AS but also offer important references for exploring new therapeutic targets, highlighting their substantial clinical applicability.
Authors
- Bin Ming
- Linrui Zhong (ORCID: https://orcid.org/0009-0005-5319-1992)
- Quan‐Bo Zhang (ORCID: https://orcid.org/0000-0001-8559-1927)
- Yufeng Qing (ORCID: https://orcid.org/0000-0001-6709-7570)
- Zeng Zhang (ORCID: https://orcid.org/0000-0002-2322-8572)
- Yanhui Li (ORCID: https://orcid.org/0000-0003-2282-7175)
- Y NI
Institutions
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fimmu.2024.1480492
- Citations
- 3
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- National Natural Science Foundation of China