The endocannabinoid anandamide prevents TH17 programming of activated T lymphocytes while preserving TH1 responses
These data suggest that AEA has the potential to block chronic inflammation without influencing crucial anti-viral and anti-microbial immune defense mechanisms, and may therefore be an attractive molecule to interfere with the establishment of chronic inflammation.
Authors
- Virna Margarita Martín Giménez (ORCID: https://orcid.org/0000-0003-2188-977X)
- Andreas Weigert
- Tom Teichmann (ORCID: https://orcid.org/0009-0009-5402-3834)
- Anastasiia Kiprina
- Maike Windbergs (ORCID: https://orcid.org/0000-0001-9475-699X)
- Walter Manucha (ORCID: https://orcid.org/0000-0002-2279-7626)
- Ralf P. Brandes (ORCID: https://orcid.org/0000-0002-8035-0048)
- XU Wen-qing (ORCID: https://orcid.org/0009-0000-6369-698X)
- Fiona Sailer
Institutions
- Goethe University Frankfurt (DE)
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Universidad Nacional de Cuyo (AR)
- Universidad Católica de Cuyo (AR)
- German Centre for Cardiovascular Research (DE)
- Instituto de Medicina y Biología Experimental de Cuyo (AR)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fphar.2024.1528759
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00