Identification of immunostimulatory activities and active compounds from sequentially extracted fractions of rhizosphere fungal fermentation broth of Atractylodes macrocephala Koidz. rhizomes
The present study demonstrated that the metabolite extracts of the rhizosphere fungi isolated from the rhizosphere soil of AMR exhibited in vitro immunoreactive activities and that these rhizosphere fungi could produce several bioactive metabolites. The crude extracts of the rhizosphere fungi may hence extend the medicinal utility of AMR and provide a basis for further development of natural plant-based immunomodulators.
Authors
- Nianxia Sun
- Zhili Han (ORCID: https://orcid.org/0009-0003-4881-9816)
- Na Lin (ORCID: https://orcid.org/0000-0002-7426-2199)
- Peng Huang (ORCID: https://orcid.org/0000-0002-0146-921X)
- Pingping Song
- Yuxin Xie (ORCID: https://orcid.org/0009-0008-3269-092X)
- Xinyuan Ni
- Dianlei Wang
- Yakun Wang (ORCID: https://orcid.org/0009-0004-4891-524X)
Institutions
- Anhui University of Traditional Chinese Medicine (CN)
- Beijing Municipal Health Commission (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fphar.2024.1460614
- Citations
- 1
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Anhui University
- Anhui University of Chinese Medicine