Spatially-resolved analyses of muscle invasive bladder cancer microenvironment unveil a distinct fibroblast cluster associated with prognosis
We assessed the spatial landscape of the MIBC microenvironment and revealed a specific FB cluster with prognostic potential. These findings offer novel insights into the spatial heterogeneity of the MIBC microenvironment and highlight its clinical significance.
Authors
- Yuting Tao (ORCID: https://orcid.org/0000-0002-2281-0640)
- Yaobang Wang
- Tianyu Li (ORCID: https://orcid.org/0000-0003-0833-8762)
- Chao Feng (ORCID: https://orcid.org/0009-0002-1893-412X)
- Liangyu He (ORCID: https://orcid.org/0000-0002-0570-7377)
- Shaomei Tang (ORCID: https://orcid.org/0000-0001-6593-593X)
- Qiuyan Wang (ORCID: https://orcid.org/0000-0001-9372-4435)
- Zhenxing Wang (ORCID: https://orcid.org/0000-0002-9395-0341)
- Han Mo (ORCID: https://orcid.org/0000-0003-1834-1746)
- Yuanliang Xie (ORCID: https://orcid.org/0000-0002-6139-3253)
- Shulin Wu
- Wuyue Song
- Zezu Qin
- Hui Liu (ORCID: https://orcid.org/0009-0003-3273-6979)
- Tao Liu (ORCID: https://orcid.org/0000-0001-9529-6550)
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Tumor Hospital of Guangxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fimmu.2024.1522582
- Citations
- 5
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region
- National Natural Science Foundation of China
- Natural Science Foundation of Guangxi Province
- Guangxi Medical University
- Specific Research Project of Guangxi for Research Bases and Talents