Unveiling the NEFH+ malignant cell subtype: Insights from single-cell RNA sequencing in prostate cancer progression and tumor microenvironment interactions
By examining the cellular heterogeneity of a unique <i>NEFH+</i> malignant cell subtype within the PCa microenvironment, we were able to disclose their reciprocal interaction with disease progression. This offers a novel viewpoint on the diagnosis and treatment of PCa.
Authors
- Zhikai Xiahou
- Changzhong Wang (ORCID: https://orcid.org/0000-0002-4136-2433)
- Fu Zhao (ORCID: https://orcid.org/0000-0002-5286-5650)
- Yan Liu (ORCID: https://orcid.org/0000-0002-2523-997X)
- Qiang Zhang (ORCID: https://orcid.org/0000-0003-3045-4444)
- Zongze Yu
- Jie Wang (ORCID: https://orcid.org/0000-0002-4673-9025)
- Zhou Sun (ORCID: https://orcid.org/0009-0000-2428-9679)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Jilin University (CN)
- Meizhou City People's Hospital (CN)
- Hubei University of Arts and Science (CN)
- Xiangyang Central Hospital (CN)
- The First People's Hospital of Jiangxia District (CN)
- Xian Yang Central Hospital (CN)
- Union Hospital (CN)
- Beijing Sport University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fimmu.2024.1517679
- Citations
- 12
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 3.42