Polygenic risk for epigenetic aging and adverse life experiences interact to predict growth in adolescent depression in a racially/ethnically diverse sample
We extend literature by identifying genetic contributions to epigenetic aging as a depression diathesis in adolescence. Findings also highlight the detrimental role of adverse life events in exacerbating genetic risk for the development of depression in adolescence.
Authors
- Kit K. Elam (ORCID: https://orcid.org/0000-0003-0319-5897)
- Jinni Su (ORCID: https://orcid.org/0000-0002-9767-1489)
- Kathryn Lemery‐Chalfant (ORCID: https://orcid.org/0000-0003-4511-6501)
- Weisiyu Abraham Qin (ORCID: https://orcid.org/0009-0003-9176-9375)
Institutions
- Indiana University Bloomington (US)
- Arizona State University (US)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fpsyt.2024.1499395
- Citations
- 1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism
- National Institute of Mental Health
- National Institute on Drug Abuse
- National Institute of Child Health and Human Development