Effect of plasma homocysteine on cardiometabolic multimorbidity among Chinese adults: a population-based and real-world evidence study
Our findings add new evidence to this field that of high level of plasma Hcy was consistently associated with higher risk of CMM among Chinses adults, with the largest effect combination of being coexisting diabetes, hypertension and coronary heart disease. These findings have implications for cardiologists that CMM can be attributable to high level of plasma Hcy, and for decision makers that Hcy has become a public threat that persistently affects cardiovascular health in humans.
Authors
- Jia Wang (ORCID: https://orcid.org/0000-0003-1916-5086)
- Jing Li (ORCID: https://orcid.org/0000-0002-2052-9302)
- Xuan Tan (ORCID: https://orcid.org/0009-0002-5182-7975)
- Yiwei Peng (ORCID: https://orcid.org/0000-0002-5014-8527)
- Jie Wang (ORCID: https://orcid.org/0000-0001-8270-1035)
- Ling Li (ORCID: https://orcid.org/0000-0002-0483-0736)
- Xiuqin Hong (ORCID: https://orcid.org/0000-0003-2803-8564)
- Minqi Li (ORCID: https://orcid.org/0009-0001-9196-3712)
- Yangyi Zhengliu
- Tianyao Long
Institutions
- Hunan Normal University (CN)
- Hunan Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fnut.2024.1522212
- Citations
- 3
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- Key Project of Research and Development Plan of Hunan Province
- National Natural Science Foundation of China
- Scientific Research Foundation of Hunan Provincial Education Department