INWORKS and Hiroshima/Nagasaki Leukaemia Results

The Hiroshima/Nagasaki (H/N) studies by the Radiation Effect Research Foundation have not shown increased leukaemia for acute doses below 200 milli-gray (mGy). By contrast the INWORKS study of leukaemia in workers stated: "This study provides strong evidence of positive associations between protracted low-dose radiation exposure and leukemia". The INWORKS study also claimed increased leukaemia, not including Chronic Lymphocytic Leukaemia, at cumulative occupational doses of less than 100 mGy. This is contrary to the expectation that the H/N studies would show more severe effects than the worker study because the doses were acute instead of chronic and because the H/N studies included children who had higher rates of radiation induced leukaemia than adults. This paper shows that the INWORKS leukaemia study is consistent with the H/N studies in showing no increase in leukaemia in the low-dose range. In addition, any increase in leukaemia is confined to Chronic Myeloid Leukaemia, possibly from high radiation dose-rates or chemicals.

Authors

Institutions

Publication Details

Journal
Dose-Response
Published
2024-10-01
DOI
https://doi.org/10.1177/15593258241303476
Citations
2
Primary Topic
Radiation Dose and Imaging
Type
article
Field-Weighted Citation Impact
0.81
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

INWORKS and Hiroshima/Nagasaki Leukaemia Results

Ken Robert Chaplin
2 citations
Dose-Response
Radiation Dose and Imaging
0.81
article

INWORKS and Hiroshima/Nagasaki Leukaemia Results

Ken Robert Chaplin
article en
2 citations

Abstract

The Hiroshima/Nagasaki (H/N) studies by the Radiation Effect Research Foundation have not shown increased leukaemia for acute doses below 200 milli-gray (mGy). By contrast the INWORKS study of leukaemia in workers stated: "This study provides strong evidence of positive associations between protracted low-dose radiation exposure and leukemia". The INWORKS study also claimed increased leukaemia, not including Chronic Lymphocytic Leukaemia, at cumulative occupational doses of less than 100 mGy. This is contrary to the expectation that the H/N studies would show more severe effects than the worker study because the doses were acute instead of chronic and because the H/N studies included children who had higher rates of radiation induced leukaemia than adults. This paper shows that the INWORKS leukaemia study is consistent with the H/N studies in showing no increase in leukaemia in the low-dose range. In addition, any increase in leukaemia is confined to Chronic Myeloid Leukaemia, possibly from high radiation dose-rates or chemicals.

Dose-ResponseVol. 22(4)
Canadian Nuclear Laboratories (CA)
Good health and well-being
Openalex Percentile: Top 24%
Radiation Dose and Imaging
0.81
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.