The Impact of Age and Sex on Fasting Plasma Glucose and Glycated Haemoglobin (HbA1c) in the Non-diabetes Population
We showed differences in HbA1c and FPG patterns with age between men and women, with implications for the diabetes diagnostic threshold for HbA1c in pre-menopausal women, the underdiagnosis of type 2 diabetes in younger women, and missed opportunities for intervention. We propose that a suggested change to HbA1c reference ranges in this group warrants serious consideration and detailed evaluation.
Authors
- Fahmy Hanna (ORCID: https://orcid.org/0000-0001-5800-1442)
- Ian Halsall
- Martin Gibson (ORCID: https://orcid.org/0000-0002-1331-1524)
- Anthony A. Fryer (ORCID: https://orcid.org/0000-0001-8678-0404)
- Lewis Green (ORCID: https://orcid.org/0000-0001-5792-5408)
- Mike Stedman (ORCID: https://orcid.org/0000-0002-0491-7823)
- Jonathan Scargill
- David P. Holland (ORCID: https://orcid.org/0000-0002-5052-1563)
- Adrian Hugh Heald (ORCID: https://orcid.org/0000-0002-9537-4050)
- Pensée Wu (ORCID: https://orcid.org/0000-0003-0011-5636)
- Kashyap Patel (ORCID: https://orcid.org/0000-0002-9240-8104)
Institutions
- University of Exeter (GB)
- Manchester Academic Health Science Centre (GB)
- University Hospitals of North Midlands NHS Trust (GB)
- St Helens and Knowsley Teaching Hospitals NHS Trust (GB)
- Salford Royal NHS Foundation Trust (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Royal Oldham Hospital (GB)
- University of Manchester (GB)
- Benchmark (United Kingdom) (GB)
- NIHR Exeter Clinical Research Facility (GB)
- Keele University (GB)
Publication Details
- Journal
- Diabetes Therapy
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1007/s13300-024-01680-w
- Citations
- 3
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 1.07