Anlotinib enhances the pro-apoptotic effect of APG-115 on acute myeloid leukemia cell lines by inhibiting the P13K/AKT signaling pathway
In vivo and in vitro experimental have shown that APG-115 combined with anlotinib can promote AML cells apoptosis and inhibit the progression of disease is independent of the p53 status.
Authors
- Dongbei Li
- Yu Cui (ORCID: https://orcid.org/0000-0002-4970-9980)
- Ruijuan He
- Cheng Cheng (ORCID: https://orcid.org/0000-0002-5007-4695)
- Chenxi Hu (ORCID: https://orcid.org/0000-0002-8397-9319)
- Xiaoli Guo (ORCID: https://orcid.org/0000-0001-8628-9711)
- Xudong Wei (ORCID: https://orcid.org/0000-0002-6289-2011)
- Rui Zhao (ORCID: https://orcid.org/0000-0003-4884-474X)
Institutions
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- Leukemia Research
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1016/j.leukres.2024.107637
- Citations
- 1
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.28