CD69 Expression is Negatively Associated With T-Cell Immunity and Predicts Antiviral Therapy Response in Chronic Hepatitis B
CD69 negatively regulates T-cell immunity during CHB, and its expression decreases with antiviral therapy. CD69 expression predicts HBeAg seroconversion in week 48. CD69 may play an important negative role in regulating T cells and affect the efficacy of antiviral therapy.
Authors
- Zexuan Huang (ORCID: https://orcid.org/0000-0002-8009-1015)
- Chunhong Liao (ORCID: https://orcid.org/0009-0008-5145-4041)
- Yuehua Huang (ORCID: https://orcid.org/0000-0002-0982-3551)
- Yanhua Bi (ORCID: https://orcid.org/0000-0003-1201-8622)
- Yurong Gu (ORCID: https://orcid.org/0000-0002-9178-8205)
- Huaping Xie
- Xiaoyan Li (ORCID: https://orcid.org/0000-0002-8807-4199)
- Hao Hu (ORCID: https://orcid.org/0000-0002-9583-2891)
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Annals of Laboratory Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3343/alm.2024.0178
- Citations
- 3
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province