Comparison of melanocortin-4 reptor and α-melanoside stimulated hormone levels in healthy female volunteers and female patients with and without sexual functional disorders related to the use of selective serotonin reaptake inhibitors
The fact that α-MSH and MCR4 play a role in the etiology of SD due to SSRI use in woman and that there was a significant difference between SSRI-SD (+) and SSRI-SD (-) groups when α-MSH and MCR4 levels were compared in fluoxetine users supports the hypothesis that serotonin may mediate SD via α-MSH and MCR4 through 5-hydroxytryptamine-2C (5-HT<sub>2C</sub>) antagonism.
Authors
- Yasir Şafak (ORCID: https://orcid.org/0000-0002-3196-5089)
- Selin Ozdemir
- Şule Kaya (ORCID: https://orcid.org/0000-0002-9659-1954)
Institutions
- State Hospital (GB)
- Istanbul 29 Mayis University (TR)
- Ankara 29 Mayis State Hospital
Publication Details
- Journal
- Sexual Medicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1093/sexmed/qfae085
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.00