CXCL4 deficiency limits M4 macrophage infiltration and attenuates hyperoxia-induced lung injury
CXCL4 contributes to hyperoxia-induced lung injury and fibrosis through modulation of cytokine release, alveolar cell proliferation, lipid metabolism, and the regulation of macrophage phenotype and function.
Authors
- Shuyu Chen (ORCID: https://orcid.org/0000-0001-5044-4281)
- Tianping Bao
- Siyuan Jia
- Yu Chen (ORCID: https://orcid.org/0000-0003-2722-9561)
- Zhaofang Tian (ORCID: https://orcid.org/0000-0001-5507-956X)
- Rong Guan
- Bingrui Yu
- Wanwen Tang
Institutions
- Xuzhou Medical College (CN)
- Huaian First People’s Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s10020-024-01043-y
- Citations
- 5
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Nanjing Medical University