Association between time to antibiotic and mortality in patients with suspected sepsis in the Emergency Department: post hoc analysis of the 1-BED randomized clinical trial
In patients with suspected sepsis presenting to the ED antibiotic administration beyond 1 h was associated with a two-fold increased 28-day in-hospital mortality. This effect persisted in patients without hypotension.
Authors
- Yonathan Freund (ORCID: https://orcid.org/0000-0002-0262-3848)
- Camille Gerlier (ORCID: https://orcid.org/0000-0003-1991-4083)
- Anne‐Laure Philippon (ORCID: https://orcid.org/0000-0002-3962-9266)
- Marta Cancella de Abreu (ORCID: https://orcid.org/0000-0001-7218-8485)
- Tabassome Simon (ORCID: https://orcid.org/0000-0002-4550-0450)
- Óscar Miró (ORCID: https://orcid.org/0000-0001-8127-166X)
- Soufiane Lebal
Institutions
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospital Clínic de Barcelona (ES)
- Pitié-Salpêtrière Hospital (FR)
- Hôpital Paris Saint-Joseph (FR)
Publication Details
- Journal
- European Journal of Emergency Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1097/mej.0000000000001212
- Citations
- 5
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.93