Plant Cell Culture-Derived Saponin Adjuvant Enhances Immune Response Against a Stabilized Human Metapneumovirus Pre-Fusion Vaccine Candidate
Our findings pave the way for a reliable, scalable, and sustainable source of pure QS-21, enabling the development of highly effective HMPV and other vaccines with significant public health impact.
Authors
- Harmjan Kuipers
- Sonja Schmit-Tillemans
- Brendan Reed (ORCID: https://orcid.org/0000-0001-9995-5736)
- Roland Zahn (ORCID: https://orcid.org/0000-0003-2822-6231)
- Boerries Brandenburg (ORCID: https://orcid.org/0000-0002-5025-3802)
- Mark A. Findeis (ORCID: https://orcid.org/0000-0003-2875-4827)
- Rebecca J. Kurnat
- Johan Verspuij
- Ana Izquierdo Gil (ORCID: https://orcid.org/0000-0001-9557-1807)
- Maarten Swart (ORCID: https://orcid.org/0000-0001-6109-0773)
- Jessica Allen (ORCID: https://orcid.org/0000-0002-0667-4116)
- Angela Hafner
- Chandresh Harjivan
- Anish Chakkumkal
Institutions
- Agenus (United States) (US)
- Janssen (Netherlands) (NL)
- Johnson & Johnson (Netherlands) (NL)
Publication Details
- Journal
- Vaccines
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3390/vaccines12121435
- Citations
- 6
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 2.32
Funders
- Johnson and Johnson