IL-33/ST2 axis mediates diesel exhaust particles-induced mast cell activation
Airborne pollutants may activate MCs to produce IL-33 via the AhR/NF-κB pathway, leading to type 2 cytokines production and enhancing MC airway epithelium-shifted migration through the autocrine or paracrine IL-33/ST2 axis.
Authors
- Wun-Hao Cheng (ORCID: https://orcid.org/0000-0003-0919-7930)
- Chih‐Ming Weng (ORCID: https://orcid.org/0000-0002-7045-6172)
- Han‐Pin Kuo (ORCID: https://orcid.org/0000-0002-3500-6723)
- Meng-Jung Lee
- Chun‐Liang Chou (ORCID: https://orcid.org/0000-0002-8061-703X)
- Bing-Chang Chen
- Tianchi Zhuang
Institutions
- Taipei Medical University Hospital (TW)
- Wan Fang Hospital (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s10020-024-01035-y
- Citations
- 2
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.48
Funders
- Taipei Medical University