Elucidating the role of gut microbiota metabolites in diabetes by employing network pharmacology
Gut microbiota metabolites primarily exert their therapeutic effects on diabetes through the IL6, AKT1, and PPARG targets. The mechanisms of gut microbiota metabolites regulating DM might involve signaling pathways such as IL-17 pathways, HIF-1 pathways and VEGF pathways.
Authors
- Kun Liu (ORCID: https://orcid.org/0000-0002-0115-7160)
- Pengyu Tao (ORCID: https://orcid.org/0000-0001-5024-8686)
- Jing Ji (ORCID: https://orcid.org/0009-0009-0775-6891)
- Weiguo Yao
- Jinlin Huo
Institutions
- Shantou University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Shanghai University of Medicine and Health Sciences (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Seventh People's Hospital of Shanghai (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s10020-024-01033-0
- Citations
- 25
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 5.85