Does bladder outflow obstruction obfuscate the traditional clinical factors that are used to assess the risk of prostate cancer at rapid‐access diagnostic clinics?

In the presence of bladder outflow obstruction, traditional predictive variables such as age, PSA density, digital rectal examination and scoring PI-RADS 4 are not associated with csPCa. This study suggests that using these predictive variables to triage patients in rapid-access clinics with a patient who has bladder outflow obstruction could lead to the overuse of invasive biopsy.