Crosstalk between CD180-overexpression macrophages and glioma cells worsens patient survival through malignant phenotype promotion and immunosuppressive regulation
This study confirmed the prognostic role of CD180 in glioma and its involvement in immunosuppressive regulation and malignant phenotype promotion. Therefore, CD180 was considered as a promising target for immunotherapeutic strategies in glioma treatment.
Authors
- Qiheng He (ORCID: https://orcid.org/0000-0001-6715-298X)
- Jizong Zhao (ORCID: https://orcid.org/0000-0001-7304-0255)
- Chenglong Liu (ORCID: https://orcid.org/0000-0002-8449-6343)
- Wei Sun (ORCID: https://orcid.org/0000-0003-1952-128X)
- Wen Wang (ORCID: https://orcid.org/0000-0001-6473-4888)
- Junsheng Li (ORCID: https://orcid.org/0000-0001-5099-9834)
- Bojian Zhang (ORCID: https://orcid.org/0000-0003-3605-3772)
- Zhiyao Zheng
- Siqi Mou
Institutions
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s10020-024-01029-w
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.24
Funders
- National Natural Science Foundation of China