Evaluation of antifungal effect of amphotericin B in comparison with nystatin on Candida species derived from patients undergoing head-and-neck radiotherapy
The present study showed that before radiotherapy, all species isolated from patients, including <i>C. albicans</i>, <i>C. tropicalis</i>, <i>and C. glabrata</i>, were sensitive to nystatin, whereas a percentage of albicans species showed resistance to amphotericin B. In the 2<sup>nd</sup> week of radiotherapy, the same as before radiotherapy, all species isolated from patients were sensitive to nystatin, whereas a percentage of albicans species showed resistance to amphotericin B. In general, the current study showed that before and after radiotherapy, the antifungal effect of nystatin is greater than amphotericin B.
Authors
- Mehrnoush Maheronnaghsh (ORCID: https://orcid.org/0000-0002-3597-6463)
- Nadia Najafizadeh
- Zahra Saberi (ORCID: https://orcid.org/0000-0001-5545-5668)
- Mina Jamshidi (ORCID: https://orcid.org/0000-0002-1944-4600)
- Faezeh Khozeimeh (ORCID: https://orcid.org/0000-0002-9193-716X)
- Parvin Dehghan (ORCID: https://orcid.org/0000-0002-0000-6643)
- Ahmad Amiri Chermahini
- Zahra Golestannejad
- Elham Faghihian
Institutions
- Isfahan University of Medical Sciences (IR)
- Kashan University of Medical Sciences (IR)
Publication Details
- Journal
- Dental Research Journal
- Published
- 2024-12-01
- DOI
- https://doi.org/10.4103/drj.drj_352_23
- Citations
- 1
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.39