Enhanced Expression of N-Cadherin, but Not of E-Cadherin, in Cutaneous Squamous Cell Carcinoma in Comparison to Basal Cell Carcinoma

Our results suggest that N-cadherin expression might contribute to the acquisition of the mesenchymal phenotype, SCC, when compared with BCC, with a high expression of E-cadherin in both tumors explaining their overall low rate of metastases; however, further research on the role of adhesion molecules in these tumors is needed.

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Publication Details

Journal
Cancers
Published
2024-12-20
DOI
https://doi.org/10.3390/cancers16244247
Citations
1
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.53

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article

Enhanced Expression of N-Cadherin, but Not of E-Cadherin, in Cutaneous Squamous Cell Carcinoma in Comparison to Basal Cell Carcinoma

Aleksandra Piotrowska, Piotr Dzięgiel, Joanna Pogorzelska‐Dyrbuś, Jacek Cezary Szepietowski et al.
1 citations
Cancers
Cancer and Skin Lesions
0.53
article

Enhanced Expression of N-Cadherin, but Not of E-Cadherin, in Cutaneous Squamous Cell Carcinoma in Comparison to Basal Cell Carcinoma

Aleksandra Piotrowska, Piotr Dzięgiel, Joanna Pogorzelska‐Dyrbuś, Jacek Cezary Szepietowski, Danuta Nowicka‐Suszko, Zdzisław Woźniak
article en
1 citations

Abstract

Our results suggest that N-cadherin expression might contribute to the acquisition of the mesenchymal phenotype, SCC, when compared with BCC, with a high expression of E-cadherin in both tumors explaining their overall low rate of metastases; however, further research on the role of adhesion molecules in these tumors is needed.

CancersVol. 16(24)
Wrocław University of Science and Technology (PL), Wroclaw Medical University (PL), AGH University of Krakow (PL)
Uniwersytet Medyczny im. Piastów Slaskich we Wroclawiu
Good health and well-being
Openalex Percentile: Top 25%
Cancer and Skin Lesions
0.53
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