Causal Associations Between Sleep Traits and Delirium: A Bidirectional Two-Sample Mendelian Randomization Study
Our bidirectional, two-sample MR analysis study did not provide definitive evidence that sleep traits may augment the susceptibility to delirium. However, the reverse MR results indicate that delirium may predispose patients to an earlier sleep-wake cycle. Additional large-scale investigations are necessary to examine the bidirectional causality between delirium and sleep traits.
Authors
- Wuhua Ma (ORCID: https://orcid.org/0000-0003-1277-1681)
- Zhi Zhang (ORCID: https://orcid.org/0000-0001-6256-9516)
- Longfei Ding (ORCID: https://orcid.org/0000-0002-7660-0876)
- Yuewen He (ORCID: https://orcid.org/0000-0002-4078-5100)
- Tong Wu (ORCID: https://orcid.org/0000-0001-6276-5197)
- Yong Wang (ORCID: https://orcid.org/0009-0008-4056-4413)
- Hao Liu (ORCID: https://orcid.org/0000-0003-4271-1567)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- Nature and Science of Sleep
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/nss.s491216
- Citations
- 5
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- National Natural Science Foundation of China
- Guangzhou Municipal Science and Technology Bureau