Hereditary spastic paraplegias: When to expect bladder dysfunction a genetic and urodynamic study
We have shown that the most common urodynamic pattern in HSP is detrusor overactivity associated with detrusor-sphincter dyssynergia, as would be expected for upper motor neuron lesions. We assessed the temporal window of onset, showing that urinary disorders are secondary to spastic gait in HSP and particularly frequent when walking capability deteriorates.
Authors
- Pauline Lallemant‐Dudek (ORCID: https://orcid.org/0000-0001-8495-1409)
- Rebecca Haddad (ORCID: https://orcid.org/0000-0002-1528-5569)
- G. Amarenco (ORCID: https://orcid.org/0000-0001-8067-7983)
- Claire Hentzen (ORCID: https://orcid.org/0000-0002-9223-4925)
- G. Robain
- P. Denys
- Anna Heinzmann (ORCID: https://orcid.org/0000-0001-8007-2597)
- Marine Guillaud‐Bataille (ORCID: https://orcid.org/0000-0003-4147-9102)
- B. Pichon
- Giulia Coarelli
- Alexandra Dürr
- Charles Joussain
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Sorbonne Université (FR)
- Hôpital Armand-Trousseau (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Pitié-Salpêtrière Hospital (FR)
- Handicap neuromusculaire : Physiopathologie, Biothérapie et Pharmacologie appliquées (FR)
- Institut du Cerveau (FR)
- Hôpital Tenon (FR)
- Groupe de Recherche Clinique en Neuro-urologie (FR)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1111/ene.70003
- Citations
- 1
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.54