Integrated Transcriptome Analysis Reveals Molecular Subtypes and ceRNA Networks in Multiple Sclerosis
Differential activation of immune pathways across MS subtypes suggests specific gene expression drives disease heterogeneity. We propose a circ_0045537/miR-196a-5p/<i>TUBA1A</i> axis in subtype C3, modulating microtubule dynamics and worsening MS severity.
Authors
- Cong Long
- Fumin Jia (ORCID: https://orcid.org/0009-0001-7862-3123)
- Zhiyong Zhang (ORCID: https://orcid.org/0000-0001-9753-0873)
- Ding Li (ORCID: https://orcid.org/0009-0001-2215-978X)
- Cen Ji
Institutions
- Anhui Agricultural University (CN)
Publication Details
- Journal
- Degenerative Neurological and Neuromuscular Disease
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/dnnd.s491211
- Citations
- 1
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.29