Investigating the complementary value of OCT to MRI in cognitive impairment in relapsing-remitting multiple sclerosis
GCIPL thinning correlates with SDMT, supporting OCT as a biomarker of cognitive dysfunction. However, GCIPL did not uniquely predict SDMT performance when including MRI measures, suggesting limited utility of OCT in predicting cognitive performance over MRI in RRMS.
Authors
- Ahmed Toosy (ORCID: https://orcid.org/0000-0002-4441-3750)
- Amy Jolly (ORCID: https://orcid.org/0000-0002-7413-9772)
- Charmaine Yam (ORCID: https://orcid.org/0000-0002-4146-2047)
- Marios Yiannakas (ORCID: https://orcid.org/0000-0003-4986-446X)
- Anna He (ORCID: https://orcid.org/0000-0002-6924-8798)
- Marco Pitteri (ORCID: https://orcid.org/0000-0001-8093-4548)
- Alan J. Thompson (ORCID: https://orcid.org/0000-0002-4333-8496)
- Suraya Mohamud
- Olga Ciccarelli (ORCID: https://orcid.org/0000-0001-7485-1367)
- Ronja Christensen (ORCID: https://orcid.org/0000-0002-5101-0896)
- Riccardo Nistri (ORCID: https://orcid.org/0000-0002-5479-8201)
- Eirini Samdanidou
Institutions
- Queen Mary University of London (GB)
- Karolinska Institutet (SE)
- National Institute for Health and Care Research (GB)
- Cleveland Clinic London (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- University College London (GB)
Publication Details
- Journal
- Multiple Sclerosis Journal
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1177/13524585241304356
- Citations
- 9
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.82
Funders
- National Institute for Health and Care Research
- University College London Hospitals NHS Foundation Trust
- Medical Research Council
- UCLH Biomedical Research Centre