Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs
Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment. CT-guided RFA achieved a significant tumor volume reduction (82.8%) and improvement in clinical signs such as nasal discharge, epistaxis, and respiratory distress, without complications. Post-RFA CT examinations demonstrated a significant decrease in Hounsfield units and tumor volume. This study has shown that CT-guided RFA is an effective cytoreductive option for minimally invasive management of nasal adenocarcinomas in dogs, particularly when traditional therapies like radiation therapy or surgery are not feasible.
Authors
- Plamena Pentcheva (ORCID: https://orcid.org/0000-0003-3464-2231)
- David Dacal-Rivas (ORCID: https://orcid.org/0000-0002-8203-0726)
- Beatriz Balañá
- Alicia Barbero-Fernández (ORCID: https://orcid.org/0000-0003-0213-6932)
- Timothy M. Fernandes (ORCID: https://orcid.org/0000-0001-9319-4200)
- María Dolores Alférez
- Pablo Gómez Ochoa (ORCID: https://orcid.org/0000-0002-9193-7661)
- Ignacio de Blas (ORCID: https://orcid.org/0000-0002-1204-4356)
- Amaia Escudero
- Andrea Corda (ORCID: https://orcid.org/0000-0002-9771-4143)
- Ignacio Rodríguez‐Pizà (ORCID: https://orcid.org/0000-0002-1339-274X)
- Lucas Gago (ORCID: https://orcid.org/0000-0002-4694-6120)
- Jorge Llinás
- Javier Caruncho
Institutions
- University of Sassari (IT)
- Universidad de Zaragoza (ES)
- Gerontologic Complex La Milagrosa (ES)
- Universitat de Barcelona (ES)
- Universidad Europea de Madrid (ES)
Publication Details
- Journal
- Animals
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3390/ani14243682
- Primary Topic
- Veterinary Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00