Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs

Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment. CT-guided RFA achieved a significant tumor volume reduction (82.8%) and improvement in clinical signs such as nasal discharge, epistaxis, and respiratory distress, without complications. Post-RFA CT examinations demonstrated a significant decrease in Hounsfield units and tumor volume. This study has shown that CT-guided RFA is an effective cytoreductive option for minimally invasive management of nasal adenocarcinomas in dogs, particularly when traditional therapies like radiation therapy or surgery are not feasible.

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Journal
Animals
Published
2024-12-20
DOI
https://doi.org/10.3390/ani14243682
Primary Topic
Veterinary Oncology Research
Type
article
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article

Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs

Plamena Pentcheva, David Dacal-Rivas, Beatriz Balañá, Alicia Barbero-Fernández et al.
Animals
Veterinary Oncology Research
article

Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs

Plamena Pentcheva, David Dacal-Rivas, Beatriz Balañá, Alicia Barbero-Fernández, Timothy M. Fernandes, María Dolores Alférez, Pablo Gómez Ochoa, Ignacio de Blas, Amaia Escudero, Andrea Corda, Ignacio Rodríguez‐Pizà, Lucas Gago, Jorge Llinás, Javier Caruncho
article en

Abstract

Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment. CT-guided RFA achieved a significant tumor volume reduction (82.8%) and improvement in clinical signs such as nasal discharge, epistaxis, and respiratory distress, without complications. Post-RFA CT examinations demonstrated a significant decrease in Hounsfield units and tumor volume. This study has shown that CT-guided RFA is an effective cytoreductive option for minimally invasive management of nasal adenocarcinomas in dogs, particularly when traditional therapies like radiation therapy or surgery are not feasible.

AnimalsVol. 14(24)
University of Sassari (IT), Universidad de Zaragoza (ES), Gerontologic Complex La Milagrosa (ES), Universitat de Barcelona (ES), Universidad Europea de Madrid (ES)
Good health and well-being
Openalex Percentile: Top 57%
Veterinary Oncology Research
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Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs — Plamena Pentcheva, David Dacal-Rivas, et al. · Animals (2024) | TGRS Research Map | TGRS