Identifying prioritization of therapeutic targets for ankylosing spondylitis: a multi-omics Mendelian randomization study
Our study found four AS-associated genes with multi-omics evidence and nine promising drug targets for AS, which may contribute to the understanding of the genetic mechanisms of AS and provide innovative perspectives into targeted therapy for AS.
Authors
- Peizeng Yang (ORCID: https://orcid.org/0000-0002-2647-6619)
- Guannan Su (ORCID: https://orcid.org/0000-0001-6411-3643)
- Qingyan Jiang
- Lingyu Dai
- Lan Xia
- Yu Gao (ORCID: https://orcid.org/0009-0000-5393-6310)
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s12967-024-05925-x
- Citations
- 8
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- Innovative Research Group Project of the National Natural Science Foundation of China