ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target
Our research established a glycolysis-associated gene signature that holds potential to assist clinicians in the personalized management of IPF. Furthermore, we identified that ANGPTL4 mediates mesothelial-mesenchymal transition, suggesting its viability as a therapeutic target for IPF treatment.
Authors
- Liping Dai
- Yuechong Xia
- Fang Zhou (ORCID: https://orcid.org/0000-0002-7955-6014)
- Hongyan Hui
- Songyun Ouyang (ORCID: https://orcid.org/0000-0003-1707-1537)
Institutions
- Zhengzhou University (CN)
- First Affiliated Hospital of Xinxiang Medical University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s12967-024-05869-2
- Citations
- 1
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- National Natural Science Foundation of China