Intraoperative Patellofemoral Kinematic Acquisition: The Design, Testing, and Validation of a Setup for Clinical Studies

<b>Background/Objectives</b>: Abnormalities in patellar tracking, often overlooked in surgical planning, have been identified as a contributing factor to total knee arthroplasty (TKA) complications, including anterior knee pain, patellar subluxation, and dislocation. This study aims to evaluate the repeatability of a novel intraoperative setup for assessing patellofemoral kinematics and its interaction with prosthesis design and positioning during surgery. This setup may support personalized alignment techniques in TKA, potentially improving surgical outcomes. <b>Methods</b>: Kinematic data were collected under both native and post-TKA conditions, and the Repeatability Coefficient (RC), Intraclass Correlation Coefficient (ICC), and Limits of Agreement of the Mean were calculated to assess measurement reliability. <b>Results</b>: RC values indicated high repeatability, with patellar flexion averaging an RC of 1°. Rotation and tilt demonstrated an RC below 1° post-mid-flexion, while patellar shift maintained an RC of approximately 1.6 mm. ICC and the extended Bland and Altman analysis showed an excellent agreement (ICC > 0.9) and an expected mean difference of zero for all the measured parameters. Measurements were consistent across both flexion and extension, and between native and post-TKA conditions. <b>Conclusions</b>: The proposed setup for intraoperative patellofemoral kinematic assessment demonstrated high repeatability and practical utility. The approach was found to be non-intrusive to patellar motion tracking and can be robustly integrated into the intraoperative workflow. This method provides a reliable approach for real-time patellar tracking, which may contribute to more personalized and precise TKA procedures, potentially reducing post-surgical dissatisfaction and complications.