Luminescent terbium(<scp>iii</scp>) probes containing an aromatic amino acid-based antenna for discrimination between adenine and guanine nucleotides
Herein we present a series of luminescent Tb(III)-probes ([Tb-Ltrp], [Tb-Ltyr], and [Tb-Lphe]) for sensing and discriminating purine nucleoside polyphosphates (NPP) based on a modified DTTA chelator appended to aromatic amino acids (Laa). The optically most effective luminescent [Tb-Ltrp] probe preferentially discriminates the guanine-NPPs over the adenine-NPPs <i>via</i> PeT-based modulation of Tb(III) luminescence within the biological concentration range.
Authors
- Ashis K. Patra (ORCID: https://orcid.org/0000-0001-8678-5774)
- Sunanda Pradhan (ORCID: https://orcid.org/0000-0002-8225-2863)
- Nitin Shukla (ORCID: https://orcid.org/0000-0001-7474-9952)
- Goutam Panigrahi (ORCID: https://orcid.org/0009-0009-1550-4328)
Institutions
- Indian Institute of Technology Kanpur (IN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1039/d4cc05232c
- Citations
- 4
- Primary Topic
- Lanthanide and Transition Metal Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Council of Scientific and Industrial Research, India
- University Grants Commission
- Science and Engineering Research Board