Ubiquitin-specific protease 7 maintains c-Myc stability to support pancreatic cancer glycolysis and tumor growth
This study sheds light on the molecular mechanisms underlying the Warburg effect in PDAC and unveils USP7 as a potential therapeutic target for improving PDAC treatment.
Authors
- Rongkun Li
- Caifeng Zou (ORCID: https://orcid.org/0000-0002-7972-0910)
- Yishen Mao
- Deliang Fu (ORCID: https://orcid.org/0009-0005-6224-6879)
- Jichun Gu
- Xi Xiao (ORCID: https://orcid.org/0000-0002-9753-6586)
- Chen Jin (ORCID: https://orcid.org/0000-0002-4330-9716)
- Hengchao Li (ORCID: https://orcid.org/0000-0003-2977-8185)
Institutions
- Jiangsu University (CN)
- Dalian Medical University (CN)
- Fudan University (CN)
- Affiliated Hospital of Jiangsu University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s12967-024-05962-6
- Citations
- 15
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 3.51
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province