Trans-splenic anterograde coil-assisted transvenous occlusion (TACATO) of bleeding gastric varices associated with gastrorenal shunts in cirrhosis
Gastric varices (GVs) affect 20% of patients with cirrhosis, with a 2-year bleeding risk of 25%. Fundal GVs, which account for 70% of cases, are associated with mortality rates of up to 55%, posing management challenges due to their complex anatomy and hemodynamics. Transjugular intrahepatic portosystemic shunt placement often fails to address fundal GV hemodynamics, leaving patients at a high risk of rebleeding. Balloon-occluded retrograde transvenous obliteration, while effective, is limited by complexity, logistical hurdles, and complications. TACATO (trans-splenic anterograde coil-assisted transvenous occlusion) provides effective secondary prophylaxis for fundal GV bleeding linked to gastrorenal shunts. It matches the efficacy of retrograde and anterograde techniques while offering faster execution, minimal side effects, and no need for specialized equipment or gastrorenal shunt size restrictions. Trans-splenic access ensured safe and straightforward access to the portal system and fundal GVs in all patients treated with TACATO.
Authors
- Paolo Angeli (ORCID: https://orcid.org/0000-0002-1913-0716)
- Alberto Zanetto (ORCID: https://orcid.org/0000-0002-6734-7178)
- Marco Senzolo (ORCID: https://orcid.org/0000-0002-7261-6520)
- Patrizia Burra (ORCID: https://orcid.org/0000-0002-8791-191X)
- Roberto Miraglia (ORCID: https://orcid.org/0000-0001-8835-0977)
- Sarah Shalaby (ORCID: https://orcid.org/0000-0002-8700-6282)
- Christopher Molvar (ORCID: https://orcid.org/0000-0002-1201-4026)
- Giulio Barbiero (ORCID: https://orcid.org/0000-0002-1157-3635)
- Ron C. Gaba (ORCID: https://orcid.org/0000-0002-6601-1576)
- Paolo Feltracco
- Michele Battistel (ORCID: https://orcid.org/0000-0003-1535-4437)
- Stefano Groff
- Lara Birbin
Institutions
- University of Padua (IT)
- Edward Hines, Jr. VA Hospital (US)
- University of Illinois Chicago (US)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IT)
Publication Details
- Journal
- JHEP Reports
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1016/j.jhepr.2024.101301
- Citations
- 3
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 1.11