Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients
NE cleaved CBG (laCBG) is present in septic shock patient serum, and %laCBG correlates with Asn347 glycosylation occupancy and composition. However, serum %laCBG did not correlate with septic shock clinical outcome.
Authors
- John G. Lewis (ORCID: https://orcid.org/0000-0003-2757-4111)
- Zeynep Sumer‐Bayraktar (ORCID: https://orcid.org/0000-0001-7064-2728)
- Leigh Donnellan (ORCID: https://orcid.org/0000-0002-0042-2065)
- Jessica H. Lee (ORCID: https://orcid.org/0000-0001-8643-1773)
- Emily J. Meyer (ORCID: https://orcid.org/0000-0002-7450-5808)
- Parul Mittal (ORCID: https://orcid.org/0000-0003-0139-9757)
- Wayne Rankin (ORCID: https://orcid.org/0000-0002-4427-9547)
- Marni Nenke
- Peter R. Hoffmann (ORCID: https://orcid.org/0000-0001-8493-2208)
- Clifford Young (ORCID: https://orcid.org/0000-0002-3945-286X)
- R. Louise Rushworth (ORCID: https://orcid.org/0000-0002-6270-747X)
- Morten Thaysen‐Andersen (ORCID: https://orcid.org/0000-0001-8327-6843)
- David J. Torpy (ORCID: https://orcid.org/0000-0002-5069-0981)
- Manuela Kingler-Hoffmann
Institutions
- Royal Adelaide Hospital (AU)
- University of South Australia (AU)
- Canterbury Health Laboratories (NZ)
- Queen Elizabeth Hospital (AU)
- The University of Notre Dame Australia (AU)
- Macquarie University (AU)
Publication Details
- Journal
- Clinica Chimica Acta
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1016/j.cca.2024.120108
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Royal Adelaide Hospital
- RACP Foundation
- Royal Adelaide Hospital Research Fund