First-Line PD-1 Blockade Combined With Chemotherapy for Stage IV Penile Squamous Cell Carcinoma: A Multicenter Retrospective Study
PD-1 blockade plus TP-based chemotherapy was effective and well tolerated, with favorable survival outcomes for patients with stage IV PSCC. High pretreatment intratumoral CD8+ T-cell infiltration may help to identify potential responders.
Authors
- Lichao Wei
- Xingli Shan
- Philippe E. Spiess (ORCID: https://orcid.org/0000-0002-5723-1972)
- Kai Yao (ORCID: https://orcid.org/0000-0001-8846-5184)
- Yanxia Shi (ORCID: https://orcid.org/0000-0002-5414-8049)
- Daming Xu
- Xin An (ORCID: https://orcid.org/0000-0003-0683-5511)
- Longbin Xiong
- Zhengtang Guo (ORCID: https://orcid.org/0000-0003-2259-9715)
- Yajian Li (ORCID: https://orcid.org/0000-0001-8057-0449)
- Huali Ma (ORCID: https://orcid.org/0000-0003-1369-2897)
- Ru Yan
- Yijun Zhang (ORCID: https://orcid.org/0000-0001-9664-7359)
- Wenjun Meng (ORCID: https://orcid.org/0000-0002-6780-8720)
- Hui Han (ORCID: https://orcid.org/0000-0002-8890-4295)
- Zike Qin
- Shengjie Guo (ORCID: https://orcid.org/0000-0001-7953-8775)
- Jiyan Liu (ORCID: https://orcid.org/0000-0003-4885-5481)
- Nianzeng Xing (ORCID: https://orcid.org/0000-0003-4370-3008)
- Linjun Hu
- Ting Xue (ORCID: https://orcid.org/0000-0001-5376-9807)
- Zhi-Ling Zhang
- Li-Juan Jiang
- Xianda Chen
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- Peking Union Medical College Hospital (CN)
- Moffitt Cancer Center (US)
- Cancer Hospital of Huanxing Chaoyang District Beijing (CN)
- Sun Yat-sen University Cancer Center (CN)
- State Key Laboratory of Biotherapy
Publication Details
- Journal
- Journal of the National Comprehensive Cancer Network
- Published
- 2024-12-20
- DOI
- https://doi.org/10.6004/jnccn.2024.7074
- Citations
- 3
- Primary Topic
- Genital Health and Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.72