Longitudinal Changes in Tenofovir and Tenofovir Diphosphate Concentrations Among Pregnant Women Using Oral PrEP for HIV Prevention: Findings From Durban, South Africa
PrEP use declined during pregnancy by all measures. Discrepancies between pillcap measurements and drug concentrations could be due to physiologic changes during pregnancy or under- or overuse of the pillcaps. Determining what drug metabolite concentrations are needed to confer protection during pregnancy is important for optimizing counseling and prevention support.
Authors
- Manjeetha Jaggernath
- Christina Psaros (ORCID: https://orcid.org/0000-0002-0705-2239)
- Ivana Beesham (ORCID: https://orcid.org/0000-0003-4889-8123)
- Craig W. Hendrix (ORCID: https://orcid.org/0000-0002-5696-8665)
- Yolandie Kriel (ORCID: https://orcid.org/0000-0003-3910-4045)
- Jessica E. Haberer (ORCID: https://orcid.org/0000-0001-5845-3190)
- Jiaying Hao (ORCID: https://orcid.org/0000-0002-1695-3696)
- David R. Bangsberg (ORCID: https://orcid.org/0000-0002-6352-8908)
- Lynn T. Matthews (ORCID: https://orcid.org/0000-0001-6167-6328)
- Patricia M. Smith (ORCID: https://orcid.org/0000-0003-4686-224X)
- Jennifer Smit (ORCID: https://orcid.org/0000-0002-5337-5995)
Institutions
- Harvard University (US)
- Johns Hopkins University (US)
- University of the Witwatersrand (ZA)
- Johns Hopkins Medicine (US)
- University of Alabama at Birmingham (US)
- Massachusetts General Hospital (US)
- Africa Health Research Institute (ZA)
- VinUniversity (VN)
Publication Details
- Journal
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1097/qai.0000000000003586
- Citations
- 2
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.78