Plasma zinc and selenium levels in adult inpatients with Lassa fever in Nigeria: A case-controlled study
Significantly low levels of zinc and selenium were observed in patients with LF compared with healthy controls, suggesting a role in susceptibility and pathogenesis. Given that zinc and selenium are essential trace elements for optimal functioning of the immune system, they may play a role in improving management outcomes.
Authors
- Timothy D. McHugh (ORCID: https://orcid.org/0000-0003-4658-8594)
- Sylvanus Okogbenin (ORCID: https://orcid.org/0000-0001-7882-8316)
- Isobella Honeyborne (ORCID: https://orcid.org/0000-0003-0596-758X)
- Joseph Okoeguale (ORCID: https://orcid.org/0009-0008-9909-4700)
- Cyril Erameh (ORCID: https://orcid.org/0000-0001-7783-2495)
- Ebenezer Oseremen Dic-Ijiewere (ORCID: https://orcid.org/0000-0001-6864-8979)
- Alimuddin Zumla (ORCID: https://orcid.org/0000-0002-5111-5735)
- Linzy Elton (ORCID: https://orcid.org/0000-0003-4270-1553)
- John Tembo
- Francine Ntoumi (ORCID: https://orcid.org/0000-0003-4748-050X)
- Festus O. Okojie
- Danny Asogun
- Najmul Haider (ORCID: https://orcid.org/0000-0002-5980-3460)
- Rizwan Ahmed
- Adam Zumla
- Reuben Eifediyi (ORCID: https://orcid.org/0009-0007-7877-3045)
- Otabor Christopher
- Ephraim Ogbainin
- Adoghe Patricia Omono
- Faith Unuabonah Huemomen
Institutions
- Bolton NHS Foundation Trust (GB)
- University Teaching Hospital (ZM)
- University of Zambia (ZM)
- Fondation Congolaise Pour La Recherche Médicale (CG)
- UCL Biomedical Research Centre (GB)
- Irrua Specialist Teaching Hospital (NG)
- University College London (GB)
- Ambrose Alli University (NG)
- Keele University (GB)
- University of Tübingen (DE)
Publication Details
- Journal
- IJID Regions
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1016/j.ijregi.2024.100553
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- European Commission
- Horizon 2020 Framework Programme
- European and Developing Countries Clinical Trials Partnership