Mendelian randomization evidence for lung function mediates the association between childhood allergies (age <16 years) and essential hypertension
A causal relationship between childhood allergies and essential hypertension was identified, with a proportion of the effect mediated by FVC. Therefore, implementing early interventions in children with allergies is imperative to mitigate the long-term risk of developing hypertension. Further research is required to identify additional risk factors as potential mediators.
Authors
- Junsen She
- Yong Hu (ORCID: https://orcid.org/0000-0003-0305-5616)
- Hefeng Huang (ORCID: https://orcid.org/0000-0003-4344-8019)
- Fang Chen (ORCID: https://orcid.org/0000-0002-5082-8960)
- Ling Gao (ORCID: https://orcid.org/0000-0003-1886-3931)
- Fei Guo
- Yuhang Long (ORCID: https://orcid.org/0000-0002-5751-805X)
- Bokang Zhou
Institutions
- Women's Hospital, School of Medicine, Zhejiang University (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Reproductive and Developmental Medicine
- Published
- 2024-12-17
- DOI
- https://doi.org/10.1097/rd9.0000000000000121
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality
- Zhejiang University
- Chinese Academy of Medical Sciences
- Shanghai Hospital Development Center
- Shanghai Clinical Research Center
- National Key Research and Development Program of China