Paget’s Disease of the Nipple: A Case Report and Review of the Literature

Paget’s disease of the breast is a particular form of the disease that occurs in 1 to 4% of breast cancers. It is characterised by an accumulation of abnormal cells known as "PAGET cells" in the epidermis of the nipple, associated with underlying glandular cancer in 82 to 100% of cases [1]. Clinically, it presents as eczematous eruptions on the nipple and areola, often unilateral. Imaging based on ultrasound mammography and magnetic resonance imaging of the breast is therefore useful in searching for underlying cancer. Its management and prognosis are conditioned by the accompanying breast cancer. Based on an observation and a review of the literature, this article sets out to explain the clinical features and therapeutic management of this disease.

Publication Details

Journal
Journal of Case Reports and Medical History
Published
2024-12-20
DOI
https://doi.org/10.54289/jcrmh2400157
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
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article

Paget’s Disease of the Nipple: A Case Report and Review of the Literature

Journal of Case Reports and Medical History
Cancer and Skin Lesions
article

Paget’s Disease of the Nipple: A Case Report and Review of the Literature

article en

Abstract

Paget’s disease of the breast is a particular form of the disease that occurs in 1 to 4% of breast cancers. It is characterised by an accumulation of abnormal cells known as "PAGET cells" in the epidermis of the nipple, associated with underlying glandular cancer in 82 to 100% of cases [1]. Clinically, it presents as eczematous eruptions on the nipple and areola, often unilateral. Imaging based on ultrasound mammography and magnetic resonance imaging of the breast is therefore useful in searching for underlying cancer. Its management and prognosis are conditioned by the accompanying breast cancer. Based on an observation and a review of the literature, this article sets out to explain the clinical features and therapeutic management of this disease.

Journal of Case Reports and Medical History
Good health and well-being
Openalex Percentile: Top 51%
Cancer and Skin Lesions
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Paget’s Disease of the Nipple: A Case Report and Review of the Literature · Journal of Case Reports and Medical History (2024) | TGRS Research Map | TGRS